Donatella Taramelli Selected Research

Artemisinins

7/2020	Safety of Artemisinin Derivatives in the First Trimester of Pregnancy: A Controversial Story.
1/2018	Artemisone and Artemiside Are Potent Panreactive Antimalarial Agents That Also Synergize Redox Imbalance in Plasmodium falciparum Transmissible Gametocyte Stages.
12/2014	Inhibition of metalloproteinase-9 secretion and gene expression by artemisinin derivatives.
10/2012	Dihydroartemisinin inhibits the human erythroid cell differentiation by altering the cell cycle.
10/2010	Selective toxicity of dihydroartemisinin on human CD34+ erythroid cell differentiation.
12/2009	Interaction of artemisinins with oxyhemoglobin Hb-FeII, Hb-FeII, carboxyHb-FeII, heme-FeII, and carboxyheme FeII: significance for mode of action and implications for therapy of cerebral malaria.
10/2007	The Fe2+-mediated decomposition, PfATP6 binding, and antimalarial activities of artemisone and other artemisinins: the unlikelihood of C-centered radicals as bioactive intermediates.

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Donatella Taramelli Research Topics

Disease

33	Malaria 01/2024 - 09/2004
10	Infections 09/2022 - 01/2003
5	Cerebral Malaria 12/2014 - 12/2009
4	Inflammation (Inflammations) 01/2018 - 01/2010
4	Hemolysis 09/2015 - 04/2005
3	Leishmaniasis 09/2022 - 01/2020
3	Necrosis 02/2021 - 07/2003
2	Wounds and Injuries (Trauma) 09/2022 - 04/2022
2	Hypoxia (Hypoxemia) 09/2022 - 01/2010
2	Neuroinflammatory Diseases 01/2020 - 08/2011
2	Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome) 01/2018 - 01/2015
1	COVID-19 04/2022
1	Stillbirth 07/2020
1	Spontaneous Abortion (Miscarriage) 07/2020
1	Alzheimer Disease (Alzheimer's Disease) 01/2020
1	Parasitic Diseases (Parasitic Disease) 01/2020
1	Myeloid Leukemia (Leukemia, Myelocytic) 07/2018
1	Skin Diseases (Skin Disease) 01/2017
1	Fever (Fevers) 07/2015
1	Acidosis 07/2015
1	Brain Hypoxia (Cerebral Hypoxia) 03/2011
1	Parasitemia 04/2005
1	Astrocytoma (Pilocytic Astrocytoma) 07/2003

Drug/Important Bio-Agent (IBA)

8	Antimalarials (Antimalarial Agents)IBA 01/2024 - 09/2004
8	artemisinin (artemisinine)IBA 01/2023 - 09/2004
7	Chloroquine (Aralen)FDA LinkGeneric 01/2023 - 05/2005
7	CytokinesIBA 04/2022 - 01/2003
7	ArtemisininsIBA 07/2020 - 10/2007
4	hemozoinIBA 01/2019 - 08/2011
3	Antiparasitic Agents (Antiparasitics)IBA 09/2022 - 03/2008
3	LipidsIBA 01/2018 - 08/2011
3	Heme (Haem)IBA 12/2009 - 09/2004
2	Amodiaquine (Camoquin)FDA Link 01/2023 - 05/2011
2	Oxygen (Dioxygen)IBA 09/2022 - 09/2004
2	IonophoresIBA 09/2022 - 09/2015
2	ChemokinesIBA 04/2022 - 10/2021
2	PeroxidesIBA 01/2016 - 10/2007
1	piperaquineIBA 01/2023
1	4-aminoquinolineIBA 01/2023
1	QuinolinesIBA 01/2023
1	Reactive Oxygen Species (Oxygen Radicals)IBA 09/2022
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 09/2022
1	Dextrans (Dextran)FDA Link 09/2022
1	Nitric Oxide (Nitrogen Monoxide)FDA Link 02/2021
1	Chemokine CXCL2IBA 02/2021
1	Interleukin-10 (Interleukin 10)IBA 01/2020
1	ATP-Binding Cassette Transporters (ABC Transporters)IBA 01/2020
1	PolyaminesIBA 01/2020
1	Apolipoprotein E4IBA 01/2020
1	ElacridarIBA 01/2020
1	InflammasomesIBA 01/2020
1	Amyloid (Amyloid Fibrils)IBA 01/2020
1	Glucose (Dextrose)FDA LinkGeneric 07/2018
1	Ribose (D-Ribose)IBA 07/2018
1	MaltoseIBA 07/2018
1	1- (5- (4- bromo- 2- chlorophenyl)furan- 2- yl)- N- ((piperidin- 4- yl)methyl)methanamineIBA 04/2018
1	methylamine (methylammonium)IBA 04/2018
1	furanIBA 04/2018
1	AntioxidantsIBA 01/2018
1	Oxidants (Oxidizing Agents)IBA 01/2018
1	4,6-dinitro-o-cresol (DNOC)IBA 01/2018
1	Oxidoreductases (Dehydrogenase)IBA 01/2018
1	EnzymesIBA 01/2018
1	DisulfidesIBA 01/2018
1	Anti-Bacterial Agents (Antibiotics)IBA 07/2016
1	artemisoneIBA 07/2016
1	LuciferasesIBA 05/2016
1	L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA 05/2016
1	Sildenafil Citrate (Viagra)FDA Link 05/2015
1	NucleotidesIBA 03/2015
1	Surface-Active Agents (Surfactants)IBA 01/2015
1	VaccinesIBA 01/2013
1	Volatile Oils (Essential Oils)IBA 07/2012
1	pro-matrix metalloproteinase 9IBA 08/2011
1	Peptide Hydrolases (Proteases)FDA Link 08/2011
1	Matrix Metalloproteinases (MMPs)IBA 08/2011
1	Matrix Metalloproteinase 9 (Gelatinase B)IBA 08/2011
1	CurcuminIBA 03/2011
1	Immunologic Factors (Immunomodulators)IBA 03/2011
1	Hydrolyzable TanninsIBA 07/2010
1	AcidsIBA 01/2010
1	Peptides (Polypeptides)IBA 01/2010
1	Oxyhemoglobins (Oxyhemoglobin)IBA 12/2009
1	Hemin (Panhematin)FDA Link 10/2009
1	7-chloro-4-aminoquinolineIBA 10/2009
1	Genetic Markers (Genetic Marker)IBA 01/2006
1	2,7-dibromocryptolepineIBA 04/2005
1	Acetylcysteine (Siran)FDA LinkGeneric 04/2005
1	Hydrogen Peroxide (Hydroperoxide)FDA LinkGeneric 04/2005
1	Membrane LipidsIBA 04/2005
1	Proteins (Proteins, Gene)FDA Link 04/2005
1	Carbon MonoxideIBA 09/2004
1	Free RadicalsIBA 09/2004
1	IronIBA 09/2004
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 07/2003
1	Vascular Cell Adhesion Molecule-1 (Vascular Cell Adhesion Molecule 1)IBA 07/2003
1	Interleukin-1beta (Interleukin 1 beta)IBA 07/2003
1	Amyloid beta-PeptidesIBA 07/2003

Therapy/Procedure

12	Therapeutics 01/2024 - 09/2009
1	Aftercare (After-Treatment) 07/2003